PACAP 27
About this Product
- SKU:
- PA-010
- Additional Names:
- PACAP 1-27, Pituitary Adenylate Cyclase-Activating Polypeptide 1-27, PACAP-38 (1-27) amide (human, mouse, ovine, porcine, rat)|PACAP-27, PACAP27, 127317-03-7, PACAP 1-27, Pituitary Adenylate Cyclase-Activating Polypeptide 1-27, HSDGIFTDSYSRYRKQMAVKKYLAAVL, PA-010, PA010
- CAS Number:
- 127317-03-7
- Extra Details:
- PACAP 27 is an endogenous neuropeptide and is the C-terminally truncated form of PACAP 38. PACAP 27 has considerable homology with vasoactive intestinal peptide (VIP) but is >100 fold more potent than VIP as an agonist of the PAC1 receptor. PACAP 27 functions in the control of anterior pituitary hormone secretion, vasodilation, adrenaline secretion, insulin secretion and immunosuppression.
- Immunogen:
- PACAP receptors
- Molecular Weight:
- 3147.65
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Hirose et al (1997) Pituitary adenylate cyclase-activating polypeptide-27 causes a biphasic chronotropic effect and atrial fibrillation in autonomically decentralized, anaesthetized dogs. J.Pharmacol.Exp.Ther. <strong>283</strong> 478 PMID: 9353360</p><p>Green et al (2006) Pituitary adenylate cyclase-activating peptide (PACAP): Assessment of dipeptidyl peptidase IV degradation, insulin-releasing activity and antidiabetic potential, Peptides <strong>27</strong>(6) 1349 https://doi.org/10.1016/j.peptides.2005.11.010</p><p>Fahrenkrug et al (2019) "VIP and PACAP receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database", IUPHAR/BPS Guide to Pharmacology doi: 10.2218/gtopdb/F67/2019.4<br></p>
- Sequence:
- H-His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 1 mg/ml in water
- Formula:
- C142H224N40O39S
