ICI 182,780
Product Sizes
5 mg
£118.00
NR-210-5MG
About this Product
- SKU:
- NR-210
- Additional Names:
- NR-210, NR 210, NR210, ZD 9238, Fulvestrant, Faslodex, i>>ICI 182780, i>>ICI-182780, i>>ICI182,780|ZD 9238, Fulvestrant, Faslodex
- CAS Number:
- 129453-61-8
- Extra Details:
- ICI 182,780 is a high affinity pure estrogen receptor antagonist, which is devoid of any partial agonism, and is also a high affinity agonist at the G protein-coupled estrogen receptor 1 (GPER), also known GPR30. ICI 182,780 inhibits MCF-7 human breast cancer cell growth in vitro and shows antitumour activity in mouse models. ICI 182,780 is a highly selective estrogen receptor downregulator, which is able to bind, block, and accelerate estrogen receptor (ER) degradation through inhibition of ER transcriptional activity. ICI 182,780 is a clinically useful option for some advanced breast cancers.
- Immunogen:
- Nuclear receptor modulators
- Molecular Weight:
- 606.77
- Physical State:
- Solid
- Purity:
- >98% by hplc, NMR conforms
- Sequence:
- 7A Alpha,17B Beta-[9-[(4,4,5,5,5-Pentafluoropentyl)sulfinyl]nonyl]estra-1,3,5(10)-triene-3,17-diol
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
