Kisspeptin 10 (rat, mouse)
Product Sizes
Kisspeptin 10 (rat, mouse)
£134.00
NR-060
About this Product
- SKU:
- NR-060
- CAS Number:
- 478507-53-8
- Extra Details:
- Kisspeptin-10 is the endogenous ligand for the rodent kisspeptin receptor (KISS1, GPR54) and is the minimal sequence of metastin (45-54) which activates GPR54 signaling. Kisspeptin has recently emerged as a key regulator of the mammalian reproductive axis while stimulation of GPR54 can also up-regulate proapoptotic genes which have tumour suppressor properties, inhibiting metastasis and invasion in mouse melanomas
- Molecular Weight:
- 1318.5
- Purity:
- >95% by HPLC
- References:
- <p>Stafford et al (2002) Identification and characterization of mouse metastasis-suppressor KiSS1 and its G-protein-coupled receptor. Cancer Res. <strong>62</strong> 5399 <a href="https://pubmed.ncbi.nlm.nih.gov/12359743/" target="_blank" rel="nofollow">PMID: 12359743</a></p><p>Navarro et al (2004) Developmental and hormonally regulated messenger ribonucleic acid expression of KiSS-1 and its putative receptor, GPR54, in rat hypothalamus and potent luteinizing hormone-releasing activity of KiSS-1 peptide. Endocrinology <strong>145</strong> 4565 <a href="https://pubmed.ncbi.nlm.nih.gov/15242985/" target="_blank" rel="nofollow">PMID: 15242985</a></p><p>Clarke et al (2015) Comprehensive Review on Kisspeptin and Its Role in Reproductive Disorders. Endocrinology and metabolism (Seoul, Korea)<strong> 30</strong>(2) 124 <a href="https://pubmed.ncbi.nlm.nih.gov/26194072/" target="_blank" rel="nofollow">PMID: 26194072</a></p>
- Sequence:
- H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Tyr-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C63H83N17O15