MOG (35-55) (rat)
About this Product
- SKU:
- NR-020
- Additional Names:
- MOG (35-55) (rat), myelin oligodendrocyte glycoprotein, MOG, encephalitogenic, multiple sclerosis, demyelination, MS, H-MEVGWYRSPFSRVVHLYRNGK-OH, MEVGWYRSPFSRVVHLYRNGK, 149635-73-4, NR-020, NR020
- CAS Number:
- 149635-73-4
- Extra Details:
- MOG (35-55) (rat) is a fragment of myelin oligodendrocyte glycoprotein (MOG), a transmembrane glycoprotein expressed at the surface of oligodendrocyte cells and on the outermost surface of the myelin sheath. MOG (35-55) (rat) is highly encephalitogenic, inducing strong T-cell and B-cell responses. As MOG (35-55) (rat) injection produces relapsing-remitting neurologic disease with clinical, histopathologic and immune similarities to multiple sclerosis, MOG induced demyelination is used as a model for MS research.
- Immunogen:
- Epitopes
- Molecular Weight:
- 2582
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Oliver et al (2003) Rat and Human Myelin Oligodendrocyte Glycoproteins Induce Experimental Autoimmune Encephalomyelitis by Different Mechanisms in C57BL/6 Mice. J. Immunol. <strong>171</strong> (1) 462 DOI: 10.4049/jimmunol.171.1.462 </p><p>Casella et al (2016) IL4 induces IL6-producing M2 macrophages associated to inhibition of neuroinflammation in vitro and in vivo. J. Neuroinflamm. <strong>13</strong> 139 https://doi.org/10.1186/s12974-016-0596-5</p>
- Sequence:
- H-Met-Glu-Val-Gly-Trp-Tyr-Arg-Ser-Pro-Phe-Ser-Arg-Val-Val-His-Leu-Tyr-Arg-Asn-Gly-Lys-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dark, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C118H177N35O29S
