Neuropeptide FF
About this Product
- SKU:
- NF-010
- Additional Names:
- Neuropeptide F, 99566-27-5, FLFQPQRF-NH2, NF-010, NF010|NPFF
- CAS Number:
- 99566-27-5
- Extra Details:
- Neuropeptide FF is an endogenous agonist at NPFF1 and NPFF2 receptors with Ki values of 2.82 and 0.21 nM respectively. Neuropeptide FF belongs to the RFamide family of peptides that are involved in a wide variety of physiological functions including central cardiovascular and neuroendocrine regulation. Neuropeptide FF also plays a role in pain regulation, modulation of opioid side effects, drug reward and anxiety.
- Immunogen:
- Neuropeptide FF receptors
- Molecular Weight:
- 1081.28
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Cline et al (2007) Central neuropeptide FF reduces feed consumption and affects hypothalamic chemistry in chicks. Neuropeptides <strong>41</strong>(6) 433 <a href="https://pubmed.ncbi.nlm.nih.gov/17936900/" target="_blank" rel="nofollow">PMID: 17936900</a></p><p>Jhamandas and Goncharuk (2013) Role of neuropeptide FF in central cardiovascular and neuroendocrine regulation. Front Endocrinol. <strong>4</strong> 8 <a href="https://pubmed.ncbi.nlm.nih.gov/23404625/" target="_blank" rel="nofollow">PMID: 23404625</a></p><p>Nguyen et al (2020) Neuropeptide FF and Its Receptors: Therapeutic Applications and Ligand Development. J Med Chem. <strong>63</strong>(21) 12387 <a href="https://pubmed.ncbi.nlm.nih.gov/32673481/" target="_blank" rel="nofollow">PMID: 32673481</a><br></p>
- Sequence:
- H-Phe-Leu-Phe-Gln-Pro-Gln-Arg-Phe-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 0.50 mg/ml in water
- Formula:
- C54H76N14O10
