Varenicline tartrate
Product Sizes
5 mg
£130.00
NA-030-5MG
About this Product
- SKU:
- NA-030
- Additional Names:
- Chantix; CP-526,555-18|Varenicline tartrate, 375815-87-5. NA-030, NA030, NA 030, Chantix; CP-526,555-18
- CAS Number:
- 375815-87-5
- Extra Details:
- Varenicline tartrate is an orally active, subtype-selective partial agonist at A Alpha4B Beta2 nicotinic receptors with Ki values of 0.06, 240, 322 and 3540 nM for A Alpha4B Beta2, A Alpha3B Beta4, A Alpha7, A Alpha1B BetaI³D Delta receptors respectively, and a full agonist at A Alpha7 neuronal nicotinic receptors. In humans, following oral administration, varenicline is almost completely absorbed and has high bioavailability (90%). Varenicline stimulates basal mesolimbic dopamine release to approximately 50% of the maximal effect of nicotine, inhibits nicotine-induced dopamine release, and reduces nicotine self-administration. Varenicline is a clinically useful smoking cessation agent.
- Immunogen:
- Nicotinic acetylcholine receptors
- Molecular Weight:
- 361.35
- Physical State:
- Solid
- Purity:
- >98% by HPLC, NMR conforms
- Sequence:
- 7,8,9,10-Tetrahydro-6H-6,10-methanoazepino[4,5-g]quinoxaline tartrate:7,8,9,10-Tetrahydro-6,10-methano-6H-pyrazino(2,3-h)(3)benzazepine tartrate
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
