Rice-memolin
Product Sizes
1 mg
£118.00
NA-010-1MG
About this Product
- SKU:
- NA-010
- Additional Names:
- VYTPG|VYTPG, NA-010, NA010, Rice-memolin, Val-Tyr-Thr-Pro-Gly
- Extra Details:
- Rice-memolin is a peptide generated by thermolysin digestion of rice bran that can improve cognitive decline. Rice-memolin corresponds to fragments of three rice protein sequences and appears to be resistant to gut proteases. In male ddY mice, rice-memolin improves cognitive decline induced by short-term high fat diet intake after oral administration in two behaviour tests, an effect inhibited by injection of methyllycaconitine (MLA), suggesting that rice-memolin acts through A Alpha7nAChR nicotinic receptors. Rice'memolin also increases neurogenesis and expression of neurotrophic factors in the hippocampus and reduces blood glucose. Rice-memolin has no effect on hippocampal mRNA expression of inflammatory cytokines such as tumour necrosis factor-A Alpha, interleukin (IL)-1A Alpha, IL-1B Beta, and IL-6. Rice-memolin is the first rice-bran-derived peptide able to improve cognitive decline.
- Immunogen:
- Nicotinic acetylcholine receptors,Plant science
- Molecular Weight:
- 535.26
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- Sequence:
- H-Val-Tyr-Thr-Pro-Gly-OH
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
