Endomorphin-1
About this Product
- SKU:
- MO-010
- Additional Names:
- EM1|Endomorphin-1, 189388-22-5, YPWF-NH2, YPWF, MO-010, MO010
- CAS Number:
- 189388-22-5
- Extra Details:
- Endomorphin 1 is an endogenous opioid peptide and one of the two endomorphins. Endomorphin 1 has exceptionally high affinity and selectivity for u opioid receptors (4000- and 15000-fold preference over D Delta and K Kappa respectively and may be the actual endogenous ligand of the u-receptor. Endomorphin 1 is distributed throughout the human, rodent and primate central and peripheral nervous systems, and has a more potent analgesic effect in acute and neuropathic pain than other opiates such as morphine, with fewer side effects.
- Immunogen:
- μ Opioid receptors
- Molecular Weight:
- 610.67
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Zadina et al (1997) A potent and selective endogenous agonist for the μ-opiate receptor. Nature <strong>386</strong> 499 PMID: 9087409</p><p>Mehta et al (2001) Endomorphin-1: Induction of Motor Behavior and Lack of Receptor Desensitization. J. Neuroscience <strong>21</strong>(12) 4436 DOI: 10.1523/JNEUROSCI.21-12-04436.2001<br></p><p>Gu et al (2017) Endomorphins: Promising Endogenous Opioid Peptides for the Development of Novel Analgesics. Neurosignals <strong>25</strong> 98 doi: 10.1159/000484909</p>
- Sequence:
- H-Tyr-Pro-Trp-Phe-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 5 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 0.60 mg/ml in water
- Formula:
- C34H38N6O5
