Melanin concentrating hormone (human, mouse, rat)
About this Product
- SKU:
- MH-010
- Additional Names:
- MCH (human, mouse, rat)|MCH (human, mouse, rat), DFDMLRCMLGRVYRPCWQV, 128315-56-0, Melanin concentrating hormone (human, mouse, rat), MH-010, MH010
- CAS Number:
- 128315-56-0
- Extra Details:
- Melanin concentrating hormone (human, mouse, rat) is the endogenous agonist at melanin concentration hormone receptors, with IC50 values of 0.3 and 1.5 nM and EC50 values of 3.9 and 0.1 nM at MCH-R1 and MCH-R2 receptors respectively. Melanin concentrating hormone receptors are expressed in the central and peripheral nervous systems and melanin concentrating hormone plays an important role in the control of feeding, energy metabolism, body weight regulation, anxiety, sleep, and reward.
- Immunogen:
- Melanin concentrating hormone receptors
- Molecular Weight:
- 2386.84
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Chung S et al. (2011) Recent updates on the melanin-concentrating hormone (MCH) and its receptor system: lessons from MCH1R antagonists. J. Mol. Neurosci. 43 115 <a href="https://pubmed.ncbi.nlm.nih.gov/20582487/" target="_blank" rel="nofollow">PMID:20582487</a></p><p>Diniz and Bittencourt (2017) The Melanin-Concentrating Hormone as an Integrative Peptide Driving Motivated Behaviors. Front Syst Neurosci. <strong>11</strong> 32 <a href="https://pubmed.ncbi.nlm.nih.gov/28611599/" target="_blank" rel="nofollow">PMID: 28611599</a></p><p>Diniz and Bittencourt (2019) The Melanin-Concentrating Hormone (MCH) System: A Tale of Two Peptides. Front Neurosci. <strong>13</strong> 1280 <a href="https://pubmed.ncbi.nlm.nih.gov/31849590/" target="_blank">PMID: 31849590</a><br></p>
- Sequence:
- H-Asp-Phe-Asp-Met-Leu-Arg-Cys*-Met-Leu-Gly-Arg-Val-Tyr-Arg-Pro-Cys*-Trp-Gln-Val-OH (disulfide bridge between cyteines 7 and 16)
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 1 mg/ml in water
- Formula:
- C105H160N30O26S4
