Staurosporine
Product Sizes
1 mg
£118.00
KS-320-1MG
About this Product
- SKU:
- KS-320
- Additional Names:
- AM 2282|KS-320, KS320, KS 320, Staurosporine, AM-2282, AM2282
- CAS Number:
- 62996-74-1
- Extra Details:
- Staurosporine is a broad spectrum kinase inhibitor, inhibiting protein kinase C, p60v-src tyrosine kinase, protein kinase A, and CaM kinase II with IC50 values of 3nM, 6 nM, 7 nM and 20 nM respectively. Staurosporine reduces nuclear myosin heavy chain 9 phosphorylation which inhibits gastric cancer cell progression in transgenic mouse models. Staurosporine inhibits cell viability and promotes apoptosis in oral and pancreatic cancer cells. Staurosporine also enhances efficiency of lentiviral transduction of human hematopoietic stem and progenitor cells, induces dopaminergic axonal outgrowth in vitro and triggers mitophagy.
- Immunogen:
- Kinases,Receptor tyrosine kinases
- Molecular Weight:
- 466.53
- Physical State:
- Solid
- Purity:
- >98% by tlc
- Sequence:
- [9S-(9A Alpha,10B Beta,11B Beta,13A Alpha)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
