PD 325901
Product Sizes
5 mg
£118.00
KS-310-5MG
About this Product
- SKU:
- KS-310
- Additional Names:
- KS-310. KS310, KS 310, PD 325901, PD-325901, PD325901, 391210-10-9
- CAS Number:
- 391210-10-9
- Extra Details:
- PD 0325901 is a potent MEK1 and MEK2 inhibitor, which inhibits MEK activity in mouse colon cells with an IC50 of 0.33 nM. PD 0325901 inhibits growth and proliferation of a variety of cancer cells in vitro, also inhibiting production of proangiogenic cytokines such as VEGF. In vivo, PD 032901 induces G1-phase cell cycle arrest and apoptosis in a cancer model and promotes myelin recovery in drug-induced demyelination in vivo in mice. PD 0325901 enhances generation of induced pluripotent stem cells (iPSCs) and in combination with CHIR 99021 and A 83-01 induces generation of ground state iPS cells from human and rat somatic cells.
- Immunogen:
- Kinases
- Molecular Weight:
- 482.2
- Physical State:
- Solid
- Purity:
- 98% by hplc. NMR conforms
- Sequence:
- N-[(2R(-))-2,3-Dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]benzamide
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
