MBP (4-14)
About this Product
- SKU:
- KS-140
- Additional Names:
- 126768-94-3, QKRPSQRSKYL, H-QKRPSQRSKYL-OH, MBP (4-14), Myelin Basic Protein Fragment (4-14), myelin basic protein, substrate for protein kinase C, assay of protein kinase C, KS-140, KS140|Myelin Basic Protein Fragment (4-14)
- CAS Number:
- 126768-94-3
- Extra Details:
- MBP (4-14), also known as Myelin Basic Protein Fragment (4-14), is a synthetic peptide having the sequence surrounding Ser(8) of myelin basic protein, and is a highly selective substrate for protein kinase C (PKC). MBP (4-14) is not phosphorylated by cyclic AMP-dependent protein kinase, casein kinases I and II, Ca2+/calmodulin-dependent protein kinase II, or phosphorylase kinase. MBP (4-14) is routinely used for the assay of protein kinase C.
- Immunogen:
- Kinases
- Molecular Weight:
- 1390.6
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Yasuda et al (1990) A synthetic peptide substrate for selective assay of protein kinase C. Biochem. Biophys. Res. Commun. <strong>166</strong>(3) 1220 <a href="https://pubmed.ncbi.nlm.nih.gov/1689574/" target="_blank" rel="nofollow">PMID: 1689574</a></p><p>Verbeek et al (2005) Protein kinase C gamma mutations in spinocerebellar ataxia 14 increase kinase activity and alter membrane targeting. Brain <strong>128</strong>(2) 436 <a href="https://pubmed.ncbi.nlm.nih.gov/15618281/" target="_blank" rel="nofollow">PMID: 15618281</a></p><p>Tandon et al (2013) New Pyrazolopyrimidine Inhibitors of Protein Kinase D as Potent Anticancer Agents for Prostate Cancer Cells. PLoS ONE <strong>8</strong>(9) e75601<a href="https://pubmed.ncbi.nlm.nih.gov/24086585/" target="_blank" rel="nofollow"> PMID: 24086585</a></p>
- Sequence:
- H-Gln-Lys-Arg-Pro-Ser-Gln-Arg-Ser-Lys-Tyr-Leu-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 5 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C60H103N21O17
