Crosstide
Product Sizes
Crosstide
£100.00
KS-070
About this Product
- SKU:
- KS-070
- CAS Number:
- 171783-05-4
- Extra Details:
- Crosstide is a synthetic peptide derived from glycogen synthase kinase-3β (GSK-3). Crosstide functions as substrate for Akt/PKB (protein kinase B) and is also recognized by MAPKAP kinase-1 and p70S6K, Crosstide also displays similar selectivity towards PKBα, PKBβ and PKBγ isoforms. The fluorescent and biotinylated version of crosstide demonstrate similar enzymic activity.
- Molecular Weight:
- 1165.2
- Purity:
- >95% by HPLC
- References:
- <p>Dai (2002) Human serum and glucocorticoid-inducible kinase-like kinase (SGKL) phosphorylates glycogen syntheses kinase 3 beta (GSK-3β) at serine-9 through direct interaction Biochem. Biophys. Res. Comm. <strong>293</strong> (4) 1191 https://doi.org/10.1016/S0006-291X(02)00349-2. </p><p>Baer et al (2005) Activation of a GST-tagged AKT2/PKBbeta. Biochim. Biophys. Acta <strong>1725</strong>(3) 340 doi:10.1016/j.bbagen.2005.04.002 </p><p>Xu et al (2005) WNK1 Activates SGK1 by a Phosphatidylinositol 3-Kinase-dependent and Non-catalytic Mechanism. J. Biol. Chem.<strong> 280</strong> 34218 doi: 10.1074/jbc.M505735200</p>
- Sequence:
- H-Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dark, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C48H77N17O17