SAMS Peptide
About this Product
- SKU:
- KS-020
- Additional Names:
- SAMS peptide, substrate, AMP-activated protein kinase, AMPK, assay, KS-020, KS020, HMRSAMSGLHLVKRR
- CAS Number:
- 125911-68-4
- Extra Details:
- SAMS peptide is a substrate for AMP-activated protein kinase (AMPK). Phosphorylated rapidly by AMPK, the Km of AMP-activated protein kinase for the SAMS peptide is higher than that for acetyl-CoA carboxylase, but the Vmax for peptide phosphorylation is 2.5 times higher than that of the parent protein. SAMS peptide therefore gives a convenient and sensitive assay for AMPK
- Immunogen:
- Kinases
- Molecular Weight:
- 1780
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Carling et al (1989) Purification and characterization of the AMP-activated protein kinase. Eur.J.Biochem. <strong>186</strong> 129 PMID: 2598924 </p><p>Davies et al (1989) Tissue distribution of the AMP-activated protein kinase, and lack of activation by cyclic-AMP-dependent protein kinase, studied using a specific and sensitive peptide assay. Eur.J.Biochem. <strong>186</strong> 123 PMID: 2574667 </p><p>Dasgupta et al (2012) The AMPK β2 subunit is required for energy homeostasis during metabolic stress. Mol. Cell. Biol. <strong>32</strong>(14) 2837 doi:10.1128/MCB.05853-11</p>
- Sequence:
- H-His-Met-Arg-Ser-Ala-Met-Ser-Gly-Leu-His-Leu-Val-Lys-Arg-Arg-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dark, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid and physiological buffers
- Formula:
- C74H131N29O18S2
