Tiger17
About this Product
- SKU:
- IM-030
- Additional Names:
- Tiger17, peptide, healer of skin wounds., macrophage, inflammatory, keratinocytes, fibroblasts, tissue remodelling phase, re-epithelialization, c[WCKPKPKPRCH-NH2], WCKPKPKPRCH, IM-030, IM030, Tiger 17. Tiger-17
- Extra Details:
- Tiger17 is an 11 amino acid peptide with a disulphide bridge between cysteines 2 and 10, which is a potent healer of skin wounds. Tiger17 was designed based on the antimicrobial peptides tigerinin-RC1 and tigerinin RC2, identified from the skin secretions of the crab eating frog Fejervarya cancrivora which also exert wound healing activity. Tiger17 exerts significant effects at various stages of wound healing progresses - the induction of macrophage recruitment to the wound site at the inflammatory reaction stage, the promotion of migration and proliferation of keratinocytes and fibroblasts, and at the tissue remodeling phase. In mouse models Tiger17 accelerates the healing of full-thickness wounds and promotes re-epithelialization of skin wounds.
- Immunogen:
- Antibacterials
- Molecular Weight:
- 1377.69
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- Tang et al (2014) A small peptide with potential ability to promote wound healing. PLoS One <strong>9</strong>(3) e92082. doi: 10.1371/journal.pone.0092082. PMID: 24647450
- Sequence:
- H-Trp-Cys-Lys-Pro-Lys-Pro-Lys-Pro-Arg-Cys-His-NH2, disulphide bridge between cysteines 2 and 10
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in DMSO as stock and physiological buffers
- Formula:
- C62H96N20O12S2
