GIP_HUMAN[22-51]
Product Sizes
GIP_HUMAN[22-51]
£235.00
GL-040
About this Product
- SKU:
- GL-040
- Extra Details:
GIP_HUMAN[22-51] is a potent proatherosclerotic peptide hormone which has a common precursor with glucose-dependent insulinotropic polypeptide (GIP). Chronic infusion of GIP_HUMAN[22-51] into ApoE-/- mice accelerates the development of aortic atherosclerotic lesions and it also increases the serum concentrations of many inflammatory and proatherogenic proteins, and induces IκB-α degradation and nuclear translocation of NF-κB in human vascular endothelial cells and macrophages. GIP_HUMAN[22-51 can also be labelled with 5-carboxyfluorescein and stable isotope labelled, please inquire.
- Molecular Weight:
- 3181.6
- Purity:
- >95% by hplc
- References:
- Masaki et al (2021) GIP_HUMAN[22-51] is a new proatherogenic peptide identified by native plasma peptidomics. Sci Rep <strong>11</strong> 14470 <a href="https://www.nature.com/articles/s41598-021-93862-w" target="_blank" rel="nofollow">https://doi.org/10.1038/s41598-021-93862-w</a>
- Sequence:
- H-Glu-Lys-Lys-Glu-Gly-His-Phe-Ser-Ala-Leu-Pro-Ser-Leu-Pro-Val-Gly-Ser-His-Ala-Lys-Val-Ser-Ser-Pro-Gln-Pro-Arg-Gly-Pro-Arg-OH
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in water
- Formula:
- C140H226N44O41