GIP (porcine)
About this Product
- SKU:
- GL-020
- Additional Names:
- GIP (porcine), Glucose-Dependent Insulinotropic Polypeptide (porcine), Gastric Inhibitory Peptide, porcine, GL-020, GL020|Glucose dependent insulinotropic polypeptide (porcine), Gastric inhibitory peptide (porcine)
- CAS Number:
- 11063-17-5
- Extra Details:
- GIP is a member of a family of structurally related hormones that includes secretin, glucagon, and vasoactive intestinal peptide. GIP (human) differs from GIP (porcine) at residues 18 and 34. GIP is secreted from specific endocrine cells (K-cells) in the epithelium of the upper part of small intestine after ingestion of food. Once released, GIP is subjected to NH2-terminal degradation by dipeptidyl peptidase-IV (DPP-IV), yielding GIP (3-42) as the primary metabolite which acts as a GIP receptor antagonist.
- Immunogen:
- Glucagon and related receptors
- Molecular Weight:
- 4975.62
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Wolffbrandt et al (1986) The effects of porcine GIP on insulin secretion and glucose clearance in the pig. Horm Metab Res. <strong>18</strong>(3) 159 doi: 10.1055/s-2007-1012260</p><p>Yamada et al (2006) Pancreatic and Extrapancreatic Effects of Gastric Inhibitory Polypeptide. Diabetes <strong>55</strong> (Supplement 2) S86 DOI: 10.2337/db06-S011</p><p>Marks (2020) The early history of GIP 1969-2000: From enterogastrone to major metabolic hormone. Peptides <strong>125</strong> 170276 https://doi.org/10.1016/j.peptides.2020.170276<br></p>
- Sequence:
- H-Tyr-Ala-Glu-Gly-Thr-Phe-Ile-Ser-Asp-Tyr-Ser-Ile-Ala-Met-Asp-Lys-Ile-Arg-Gln-Gln-Asp-Phe-Val-Asn-Trp-Leu-Leu-Ala-Gln-Lys-Gly-Lys-Lys-Ser-Asp-Trp-Lys-His-Asn-Ile-Thr-Gln-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in water
- Formula:
- C225H342N60O66S
