Obestatin (rat)
About this Product
- SKU:
- GH-130
- Additional Names:
- H-FNAPFDVGIKLSGAQYQQHGRAL-NH2, FNAPFDVGIKLSGAQYQQHGRAL-NH2, 869705-22-6, obestatin, proghrelin, orphan G protein-coupled receptor, GPR39 , hormone, GH-130, GH130
- CAS Number:
- 869705-22-6
- Extra Details:
- Similarly to ghrelin, obestatin is derived from the proteolytic cleavage of proghrelin and binds to the orphan G protein-coupled receptor GPR39 to suppress food intake, inhibit jejunal contraction and decrease body-weight gain in rats, contrary to the appetite-stimulating effects of ghrelin. Thus two peptide hormones with opposing action in weight regulation are derived from the same ghrelin gene.
- Immunogen:
- Orphan 7-TM receptors
- Molecular Weight:
- 2516.8
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Zhang et al (2005) Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake. Science <strong>310</strong> 996 PMID: 16284174 </p><p>Nogueiras and Tschop (2005) Biomedicine. Separation of conjoined hormones yields appetite rivals. Science <strong>310</strong> 985 PMID: 16284170</p><p>Pan and Kastin (2006) Differential BBB interactions of three ingestive peptides: obestatin, ghrelin, and adiponectin. Peptides 27 911 PMID: 16476508</p>
- Sequence:
- H-Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Ala-Gln-Tyr-Gln-Gln-His-Gly-Arg-Ala-Leu-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dessicated and frozen in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C114H174N34O31
