GLP-1 (9-36) amide
Product Sizes
GLP-1 (9-36) amide
£200.00
GH-040
About this Product
- SKU:
- GH-040
- Additional Names:
- Glucagon-like peptide-1 (9-36) amide
- CAS Number:
- 161748-29-4
- Extra Details:
- GLP-1 (9-36) amide, or Glucagon-like peptide-1 (9-36) amide, is a glucoregulatory peptide and the human N-terminally truncated major metabolite of glucagon-like peptide GLP-1 (7-36) amide, formed by dipeptidyl peptidase-IV (DPP IV) cleavage. GLP-1 (9-36) amide acts as an antagonist at the human GLP-1 receptor, inhibits hepatic glucose production and is a weak insulinotropic agent.
- Molecular Weight:
- 3089.4
- Purity:
- >95% by HPLC
- References:
- <p>Knudsen and Pridal (1996) Glucagon-like peptide-1-(9-36) amide is a major metabolite of glucagon-like peptide-1-(7-36) amide after in vivo administration to dogs, and it acts as an antagonist on the pancreatic receptor. Eur. J. Pharmacol. <strong>318</strong>(2-3) 429 <a href="https://pubmed.ncbi.nlm.nih.gov/9016935/" target="_blank" rel="nofollow">PMID: 9016935</a></p><p>Elahi et al (2008) GLP-1 (9-36) amide, cleavage product of GLP-1 (7-36) amide, is a glucoregulatory peptide. Obesity <strong>16</strong>(7) 1501 <a href="https://pubmed.ncbi.nlm.nih.gov/18421270/" target="_blank" rel="nofollow">PMID: 18421270</a></p><p>Sathananthan et al (2013) Direct Effects of Exendin-(9,39) and GLP-1-(9,36)amide on Insulin Action, β-Cell Function, and Glucose Metabolism in Nondiabetic Subjects. Diabetes<strong> 62</strong>(8) 2752 <a href="https://pubmed.ncbi.nlm.nih.gov/23545708/" target="_blank" rel="nofollow">PMID: 23545708</a></p>
- Sequence:
- H-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store dry, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C140H214N36O43