WKYMVM
About this Product
- SKU:
- FR-030
- Additional Names:
- W-peptide|WKYMVM, 187986-11-4, W-peptide, FR-030
- CAS Number:
- 187986-11-4
- Extra Details:
- WKYMVM is a potent N-formyl peptide receptor agonist. WKYMVM activates neutrophils through FPRL1/lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. WKYMVM also activates several leukocyte effector functions such as chemotaxis, mobilization of complement receptor-3, and can activate NADPH oxidase
- Immunogen:
- Formyl peptide receptors
- Molecular Weight:
- 856.11
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Christophe et al (2001) The synthetic peptide Trp-Lys-Tyr-Met-Val-Met-NH2 specifically activates neutrophils through FPRL1/Lipoxin A4 receptors and is an agonist for the orphan monocyte-expressed chemoattractant receptor FPRL2. J.Biol.Chem. 276 21585 <a href="https://pubmed.ncbi.nlm.nih.gov/11285256/" target="_blank" rel="nofollow">PMID: 11285256</a></p><p>Christophe et al (2002) Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1 /LXA4R, is not affected by lipoxin. Scand.J.Immunol. <strong>56</strong> 470 <a href="https://pubmed.ncbi.nlm.nih.gov/12410796/" target="_blank" rel="nofollow">PMID: 12410796</a></p><p>Karlsson et al (2007) Ability of monocyte-derived dendritic cells to secrete oxygen radicals in response to formyl peptide receptor family agonists compared to that of myeloid and plasmacytoid dendritic cells. Clin Vaccine Immunol. <strong>14</strong>(3) 328 <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1828863/" target="_blank" rel="nofollow">PMID: 17215332</a></p>
- Sequence:
- H-Trp-Lys-Tyr-Met-Val-Met-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 0.60 mg/ml in water
- Formula:
- C41H61N9O7S2
