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Proteins and Peptides

SFKEELDKYFKNHTSP

Product Sizes
1 mg
£170.00
EP-020-1MG
Academic Pricing
Please contact us for academic pricing.
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About this Product
SKU:
EP-020
Additional Names:
EP-020, SFKEELDKYFKNHTSP, 1147SFKEELDKYFKNHTSP1162, truncated P4|truncated P4, 1147SFKEELDKYFKNHTSP1162
Extra Details:
SFKEELDKYFKNHTSP is a truncated peptide derived from the P4 peptide of the S2 subunit of the S protein of SARS-CoV-2 which has the the amino acid sequence DPLQPELDSFKEELDKYFKNHTSPDVDLGDIS, corresponding to residues 1139-1170. The P4 peptide is located in the linker region between heptad repeat 1 (HR1) and heptad repeat 2 (HR2) and is highly conserved among SARS-CoV, BatCoV RaTG13, SARS-CoV-2 and recent SARS-CoV-2 variants. Antibodies targeting the peptide SFKEELDKYFKNHTSP can neutralize both SARS-CoV-2 and SARS-CoV by preventing fusion between the virus and the cell membrane.
Immunogen:
Antivirals,Epitopes
Molecular Weight:
1970.16
Physical State:
Freeze dried solid
Purity:
>95%
References:
Li et al (2021) A novel linear and broadly neutralizing peptide in the SARS-CoV-2 S2 protein for universal vaccine development. Cell Mol Immunol. <strong>18</strong>(11) 2563 PMID: 34645942
Sequence:
H-Ser-Phe-Lys-Glu-Glu-Leu-Asp-Lys-Tyr-Phe-Lys-Asn-His-Thr-Ser-Pro-OH
Shipping Conditions:
Blue Ice
Storage Conditions:
Store dry, frozen and in the dark
Size:
1 mg
Supplier:
Isca Biochemicals
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
Solubility:
Soluble in water
Formula:
C90 H132N22O28