OVA (257-264)
About this Product
- SKU:
- EP-010
- Additional Names:
- OVA (257-264), Ovalbumin (257-264) (chicken), 138831-86-4, SIINFEKL, EP-010, EP010|Ovalbumin (257-264) (chicken)
- CAS Number:
- 138831-86-4
- Extra Details:
- OVA (257-264) is a class I (Kb)-restricted peptide epitope of ovalbumin presented by the class I MHC (major histocompatibility complex) molecule, H-2Kb (class I genes of the mouse MHC). OVA(257-264) is an antigenic peptide and has been used to trigger T cell activation in immunology studies. OVA (257-264) has been used to sensitize mice to generate an asthmatic model, in the stimulation of splenocytes and for treating dendritic cells to be used as a positive controls in cross-presentation studies.
- Immunogen:
- Epitopes
- Molecular Weight:
- 963.13
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Lipford et al (1993) Primary in vivo responses to ovalbumin. Probing the predictive value of the Kb binding motif. J. Immunology <strong>150</strong>(4) 1212</p><p>Wick and Pfeifer (1996), Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur. J. Immunol.<strong> 26</strong> 2790 https://doi.org/10.1002/eji.1830261135</p><p>Karandikar et al (2019) New epitopes in ovalbumin provide insights for cancer neoepitopes. JCI Insight. <strong>5</strong>(8) e127882 doi:10.1172/jci.insight.127882</p>
- Sequence:
- H-Ser-Ile-Ile-Asn-Phe-Glu-Lys-Leu-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in any buffer > pH6
- Formula:
- C45H74N10O13
