BMP-2 derived peptide
Product Sizes
BMP-2 derived peptide
£200.00
EI-030
About this Product
- SKU:
- EI-030
- Additional Names:
- Bone morphogenetic protein 2 derived peptide
- Extra Details:
- BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification.
- Molecular Weight:
- 2334.76
- Purity:
- >95% by HPLC
- References:
- <p>Saito et al (2003) Activation of osteo-progenitor cells by a novel synthetic peptide derived from the bone morphogenetic protein-2 knuckle epitope. Biochim. Biophys. Acta. <strong>1651</strong>(1-2) 60 <a href="https://pubmed.ncbi.nlm.nih.gov/14499589/" target="_blank" rel="nofollow">PMID: 14499589</a></p><p>Balakin et al (2019) Quantitative analysis of BMP-2 derived peptide covalently grafted onto oxidized detonation nanodiamonds. Carbon <strong>152</strong> 740 ISSN 0008-6223<a href="https://www.sciencedirect.com/science/article/abs/pii/S0008622319305378?via%3Dihub" target="_blank" rel="nofollow"> https://doi.org/10.1016/j.carbon.2019.05.064</a></p>
- Sequence:
- H-Lys-Ile-Pro-Lys-Ala-Ser-Ser-Val-Pro-Thr-Glu-Leu-Ser-Ala-Ile-Ser-Thr-Leu-Tyr-Leu-Gly-Gly-Cys-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in water
- Formula:
- C104H176N26O32S