SBP1
About this Product
- SKU:
- CV-050
- Additional Names:
- H-IEEQAKTFLDKFNHEAEDLFYQS-NH2, IEEQAKTFLDKFNHEAEDLFYQS-NH2, SBP1, angiotensin-converting enzyme 2, ACE2, severe acute respiratory syndrome coronavirus, SARS-CoV-2, spike protein, SARS-CoV, COVID-19, CV-050, CV050
- Extra Details:
- SBP1 is a 23 amino acid fragment of the angiotensin-converting enzyme 2 (ACE2) peptidase domain (PD) A Alpha1 helix, a key domain for the interaction of ACE2 with the severe acute respiratory syndrome coronavirus receptor binding domain (SARS-CoV-2-RBD). SBP1 binds to the SARS-CoV-2-RBD with an affinity comparable with the corresponding spike protein of SARS-CoV, and can potentially block the mechanism by which SARS-CoV-2 enters into cells. SBP1 offers an opportunity for therapeutic intervention in COVID-19.
- Immunogen:
- Protein-protein interactions,Angiotensin converting enzyme,Antivirals
- Molecular Weight:
- 2802.05
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Zhang et al (2020) The first-in-class peptide binder to the SARS-CoV-2 spike protein. bioRxiv 2020.03.19.999318; doi: https://doi.org/10.1101/2020.03.19.999318 </p><p>Zhang et al (2020) Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD. bioRxiv 2020.03.19.999318; doi: https://doi.org/10.1101/2020.03.19.999318</p>
- Sequence:
- H-Ile-Glu-Glu-Gln-Ala-Lys-Thr-Phe-Leu-Asp-Lys-Phe-Asn-His-Glu-Ala-Glu-Asp-Leu-Phe-Tyr-Gln-Ser-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 1 mg/ml in water
- Formula:
- C127H185N31O41
