Nitazoxanide
Product Sizes
10 mg
£83.00
CV-020-10MG
About this Product
- SKU:
- CV-020
- Additional Names:
- Nitazoxanide, antiparasitic, antiviral drug, coronavirus protease , 55981-09-4, CV-020, CV020, NTZ|NTZ
- CAS Number:
- 55981-09-4
- Extra Details:
- Nitazoxanide is a broad-spectrum antiparasitic and broad-spectrum antiviral drug that is used clinically in the treatment of various helminthic, protozoal, and viral infections. The anti-protozoal activity of nitazoxanide is due to interference with the pyruvate:ferredoxin oxidoreductase (PFOR) enzyme-dependent electron transfer reaction required for anaerobic energy metabolism. As an antiviral agent nitazoxanide is active against many RNA and DNA viruses including influenza, hepatitis B and C, RSV and dengue and shows inhibitory efficacy against the coronavirus protease in vitro.
- Immunogen:
- Other proteases,Antiparasitics
- Molecular Weight:
- 307.3
- Physical State:
- Lyophilized
- Purity:
- >98% by hplc, NMR conforms to standard
- References:
- <p>Sisson et al (2002) Enzymes associated with reductive activation and action of nitazoxanide, nitrofurans, and metronidazole in Helicobacter pylori. Antimicrob. Agents Chemother. <strong>46</strong>(7) 2116 doi:10.1128/aac.46.7.2116-2123.2002 </p><p>Di Santo and Ehrisman (2013) Research perspective: potential role of nitazoxanide in ovarian cancer treatment. Old drug, new purpose? Cancers <strong>5</strong>(3) 1163 doi: 10.3390/cancers5031163. PMID: 24202339 </p><p>Liu et al (2020) Research and Development on Therapeutic Agents and Vaccines for COVID-19 and Related Human Coronavirus Diseases. ACS Cent. Sci. <strong>6</strong>(3) 315 https://doi.org/10.1021/acscentsci.0c00272</p>
- Sequence:
- O-[N-(5-Nitrothiazol-2-yl)carbamoyl]phenyl acetate
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 10 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
- Solubility:
- Soluble in DMSO to 50mg/ml
- Formula:
- C12H9N3O5S
