CGRP (8-37) (human)
About this Product
- SKU:
- CG-030
- Additional Names:
- CGRP 8-37 (human), 119911-68-1, VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2, VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF, hCGRP-(8-37), CG-030, CG030|CGRP 8-37 (human), Calcitonin Gene-Related Peptide 8-37 (human), hCGRP-(8-37)
- CAS Number:
- 119911-68-1
- Extra Details:
- CGRP (8-37) (human) is a fragment of calcitonin gene related peptide (CGRP) and is a selective, competetive antagonist of CGRP receptors. CGRP (8-37) (human) acts as a vasodilator agent which is active in vivo and in vitro and can also block pain and migraine headache in animal models.
- Immunogen:
- Calcitonin and related receptors
- Molecular Weight:
- 3125.64
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Chiba et al (1989) Calcitonin gene-related peptide receptor antagonist human CGRP-(8-37). Am J Physiol. <strong>256</strong>(2 Pt 1) E331 doi: 10.1152/ajpendo.1989.256.2.E331. PMID: 2537579.</p><p>Wisskirchen et al (1998) Pharmacological characterization of CGRP receptors mediating relaxation of the rat pulmonary artery and inhibition of twitch responses of the rat vas deferens. Br.J.Pharmacol. <strong>123</strong> 1673 PMID: 9605575</p><p>Hay and Walker (2017) CGRP and its receptors. Headache: The Journal of Head and Face Pain.<strong> 57</strong> 625 https://doi.org/10.1111/head.13064<br></p>
- Sequence:
- H-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble to 0.50 mg/ml in water
- Formula:
- C139H230N44O38
