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Proteins and Peptides

AM 251

Product Sizes
10 mg
£130.00
CB-010-10MG
About this Product
SKU:
CB-010
Additional Names:
AM 251, AM251, AM-251, 183232-66-8, CB-010, CB1010, CB 010
CAS Number:
183232-66-8
Extra Details:
AM 251 is a potent CB1 receptor inverse agonist, with an IC50 of 8 nM at CB1 and 306-fold selectivity over CB2 receptors. AM 251 is also a GPR55 agonist with an EC50 of 39 nM and a u-opioid receptor antagonist with a Ki of 251 nM. AM251 displays anorectic, antidepressant-like and analgesic effects in animals. AM251 can attenuate or reverse the nociceptive - hyperalgesia and allodynia - behaviours induced by burn injury.
Immunogen:
μ Opioid receptors,Cannabinoid receptors
Molecular Weight:
555.24
Physical State:
Solid
Purity:
98% by TLC , NMR conforms
Sequence:
N-(Piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide
Shipping Conditions:
Blue Ice
Supplier:
Isca Biochemicals
Type:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules