VIRIP
Product Sizes
1 mg
£189.00
AV-020-1MG
About this Product
- SKU:
- AV-020
- Additional Names:
- VIRIP, AV-020, AV020, LEAIPMSIPPEVKFNKPFVF, VIRus Inhibitory Peptide, VIR-4|VIRus Inhibitory Peptide, VIR-4
- Extra Details:
- VIRIP is a natural subfragment of A Alpha1-antitrypsin (A Alpha1-AT) and is a broad-based inhibitor of HIV-1. VIRIP was identified from screening a human haemofiltrate derived library and corresponds to residues 353-37 of A Alpha1-AT, which is the most abundant circulating serine protease inhibitor. VIRIP directly targets the highly conserved viral gp41 fusion peptide to inhibit HIV-1 entry and inhibits a wide variety of HIV-1 strains including variants resistant to protease and reverse transcriptase inhibitors. VIRIP has little or no effect on infection by virions containing HIV-2, SIV, MLV, or VSV env proteins, or by other pathogens such as ebola, herpes simplex or respiratory syncytial virus.
- Immunogen:
- Antivirals
- Molecular Weight:
- 2302.24
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- Sequence:
- H-Leu-Glu-Ala-Ile-Pro-Met-Ser-Ile-Pro-Pro-Glu-Val-Lys-Phe-Asn-Lys-Pro-Phe-Val-Phe-OH
- Shipping Conditions:
- Blue Ice
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
