Melittin, C-terminal cysteine labelled
About this Product
- SKU:
- AM-210
- Additional Names:
- H-GIGAVLKVLTTGLPALISWIKRKRQQC-NH2, GIGAVLKVLTTGLPALISWIKRKRQQC, Melittin, maleimide linked tag, fluorescent, biotinylated, AM-210, AM210
- Extra Details:
- Melittin, C-terminal cysteine labelled is synthetic melittin with an extra cysteine residue at the C terminal. Melittin is a cationic, haemolytic component of honey bee venom used to study cell and liposome lysis. Melittin is a positively charged, amphipathic 26-amino-acid peptide that associates with the phospholipids of membrane bilayers, causing cell death by forming transmembrane toroidal pores at nanomolar concentrations. Melittin, C-terminal cysteine labelled, can be labelled with any maleimide linked tag to generate fluorescent or biotinylated derivatives.
- Immunogen:
- Antibacterials
- Molecular Weight:
- 2949.63
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Fukushima et al (1998) Melittin, a metabostatic peptide inhibiting Gs activity. Peptides <strong>5</strong> 811 PMID: 9663445</p><p>Shi et al (2016) Antimicrobial peptide melittin against Xanthomonas oryzae pv. oryzae, the bacterial leaf blight pathogen in rice. Appl. Microbiol. Biotechnol. <strong>100</strong>, 5059 https://doi.org/10.1007/s00253-016-7400-4</p><p>Duffy et al (2020) Honeybee venom and melittin suppress growth factor receptor activation in HER2-enriched and triple-negative breast cancer. Precis. Onc. <strong>4</strong> 24 https://doi.org/10.1038/s41698-020-00129-0</p>
- Sequence:
- H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-Cys-NH2
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid and physiological buffers
- Formula:
- C134H234N40O32S
