CATH-2 (chicken)
Product Sizes
CATH-2 (chicken)
£235.00
AM-170
About this Product
- SKU:
- AM-170
- Extra Details:
- CATH-2 (chicken) is one of four cathelicidins which have been identified in chickens. Cathelicidins constitute a family of host defense peptides (HDPs) and play an important role during the innate immune response and CATH-2 displays strong antimicrobial activities against many different pathogens including gram-positive and gram-negative bacteria and fungi. In addition, CATH-2 has been shown to have immunomodulatory capacities.
- Molecular Weight:
- 3206.9
- Purity:
- >95% by HPLC
- References:
- <p>Cuperus et al (2013) Avian host defense peptides. Develop. Comp. Immunol. <strong>41</strong>(3) 352 <a href="https://pubmed.ncbi.nlm.nih.gov/24583933/" target="_blank" rel="nofollow">PMID: 24583933</a></p><p>Ordonez et al (2014) Fungicidal Mechanisms of Cathelicidins LL-37 and CATH-2 Revealed by Live-Cell Imaging. Antimicrob. Agents Chemother. <strong>58</strong>(4) 2240 <a href="https://pubmed.ncbi.nlm.nih.gov/24492359/" target="_blank" rel="nofollow">PMID: 24492359</a></p><p>Scheenstra et al (2019) Cathelicidins PMAP-36, LL-37 and CATH-2 are similar peptides with different modes of action. Sci Rep <strong>9 </strong>4780 <a href="https://pubmed.ncbi.nlm.nih.gov/30886247/" target="_blank" rel="nofollow">PMID: 30886247</a></p>
- Sequence:
- H-Arg-Phe-Gly-Arg-Phe-Leu-Arg-Lys-Ile-Arg-Arg-Phe-Arg-Pro-Lys-Val-Thr-Ile-Thr-Ile-Gln-Gly-Ser-Ala-Arg-Phe-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Solublie in dilute acid and physiological buffers
- Formula:
- C147H245N51O30