Parasin I
About this Product
- SKU:
- AM-130
- Additional Names:
- 219552-69-9, H-KGRGKQGGKVRAKAKTRSS-OH, KGRGKQGGKVRAKAKTRSS, Parasin I , amphipathic, antimicrobial peptide
- CAS Number:
- 219552-69-9
- Extra Details:
- Parasin I is an amphipathic antimicrobial peptide derived from the N-terminus of histone H2A of the catfish Parasilurus asotus. Parasin I has a wide antimicrobial activity and is about 12-100 times more potent than magainin 2 against a wide spectrum of microorganisms, without any hemolytic activity. In response to epidermal injury the catfish secretes parasin I into the epithelial mucosal layer, suggesting that it produces parasin I from its histone H2A by a specific protease upon injury to protect against invasion by microorganisms.
- Immunogen:
- Antibacterials
- Molecular Weight:
- 2000.4
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Park et al (1998) Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS Lett. 1998 <strong>437</strong>(3) 258 <a href="https://pubmed.ncbi.nlm.nih.gov/9824303/" target="_blank" rel="nofollow">PMID: 9824303</a></p><p>Koo et al (2008) Structure-activity relations of parasin I, a histone H2A-derived antimicrobial peptide. Peptides <strong>29</strong>(7) 1102 <a href="https://pubmed.ncbi.nlm.nih.gov/18406495/" target="_blank" rel="nofollow">PMID: 18406495</a></p><p>Zhao (2015) Characterization of bioactive recombinant antimicrobial peptide parasin I fused with human lysozyme expressed in the yeast Pichia pastoris system. Enzyme Microb. Technol. <strong>77</strong> 61 <a href="https://pubmed.ncbi.nlm.nih.gov/26138401/" target="_blank" rel="nofollow">PMID: 26138401</a></p><p><a href="https://pubchem.ncbi.nlm.nih.gov/compound/Parasin-I" target="_blank" rel="nofollow">PubChem - Parasin I</a><br></p>
- Sequence:
- H-Lys-Gly-Arg-Gly-Lys-Gln-Gly-Gly-Lys-Val-Arg-Ala-Lys-Ala-Lys-Thr-Arg-Ser-Ser-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dry, dark and frozen
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C82H154N34O24
