Histatin 3
About this Product
- SKU:
- AM-090
- Additional Names:
- H-DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN-OH, DSHAKRHHGYKRKFHEKHHSHRGYRSNYLYDN, Histatin 3, antimicrobial, innate immune system, AM-090, AM090
- Extra Details:
- Histatin 3 is a 32 amino acid histidine-rich peptide found in human saliva. Histatins function as antimicrobial peptides and are important components of the innate immune system. Histatin 3 has broad spectrum antimicrobial action including activity against gram positive and gram negative bacteria, fungi including Candida albicans and against the human protozoan parasite Leishania. Histatin 3 is post-translationally cleaved to form Histatin 5 and Histatin 8
- Immunogen:
- Antibacterials,Antifungals
- Molecular Weight:
- 4062.4
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Fitzgerald et al (2003) Binding, internalisation and degradation of histatin 3 in histatin-resistant derivatives of Candida albicans. FEMS Microbiol. Lett. <strong>220</strong>(2) 247 https://doi.org/10.1016/S0378-1097(03)00121-6 </p><p>Oudhoff et al (2008) Histatins are the major wound-closure stimulating factors in human saliva as identified in a cell culture assay. FASEB J. <strong>22</strong>(11) 3805 DOI:10.1096/fj.08-112003 </p><p>Hemadi et al (2017) Salivary proteins and microbiota as biomarkers for early childhood caries risk assessment. Int. J. Oral Sci.<strong>9</strong>, e1 https://doi.org/10.1038/ijos.2017.35</p>
- Sequence:
- H-Asp-Ser-His-Ala-Lys-Arg-His-His-Gly-Tyr-Lys-Arg-Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr-Arg-Ser-Asn-Tyr-Leu-Tyr-Asp-Asn-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store desiccated, frozen and in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C178H258N64O48
