Indolicidin
Product Sizes
Indolicidin
£141.00
AM-070
About this Product
- SKU:
- AM-070
- CAS Number:
- 140896-21-5
- Extra Details:
- Indolicidin is a 13 amino acid cationic cathelicidin family anti-microbial peptide (AMP) isolated from the cytoplasmic granules of bovine neutrophils. Indolicidin exhibits membrane permeabilization effects and antimicrobial activity against a wide spectrum of pathogens which include gram-positive and gram-negative bacteria, fungi, protozoa and the HIV-1 virus. Indolicidin is also an immune system modulator and an inhibitor of aminoglycoside antibiotic resistance enzymes.
- Molecular Weight:
- 1906.3
- Purity:
- >95% by HPLC
- References:
- <p>Subbalakshmi and Sitaram (1998) Mechanism of antimicrobial action of indolicidin. FEMS Microbiol. Lett. <strong>160</strong>(1) 91 doi:10.1111/j.1574-6968.1998.tb12896.x </p><p>Sitaram et al (2003) Indolicidin, a 13-residue basic antimicrobial peptide rich in tryptophan and proline, interacts with Ca(2+)-calmodulin. Biochem. Biophys. Res. Commun. <strong>309</strong>(4) 879 doi:10.1016/j.bbrc.2003.08.095 </p><p>Tsai et al (2009) Coupling Molecular Dynamics Simulations with Experiments for the Rational Design of Indolicidin-Analogous Antimicrobial Peptides. J. Mol. Biol. <strong>392</strong>(3) 837 https://doi.org/10.1016/j.jmb.2009.06.071.</p>
- Sequence:
- H-Ile-Leu-Pro-Trp-Lys-Trp-Pro-Trp-Trp-Pro-Trp-Arg-Arg-NH2
- Shipping Conditions:
- Ambient
- Storage Conditions:
- Store desiccated and frozen in the dark
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Solubility:
- Soluble in dilute acid
- Formula:
- C100H132N26O13