LL 37 (13-37) (human)
About this Product
- SKU:
- AM-005
- Additional Names:
- H-IGKEFKRIVQRIKDFLRNLVPRTES-OH, IGKEFKRIVQRIKDFLRNLVPRTES, LL 37 (13-37) (human), IG 27, antimicrobial, antifungal, antiviral activity, cancer, LL37 (13-37) (human), AM-005, AM005|IG 27
- Extra Details:
- LL 37 (13-37) (human), also known as IG 27, is a peptide fragment composed of the C-terminal residues 13-37 of the antimicrobial peptide LL37 [AM-001]. LL37 (13-37) has been show to have antibacterial activity against E. coli, antifungal activity against C. albicans and antiviral activity, blocking the action of HIV-1 reverse transcriptase. LL 37 (13-37) is also active against cancer cells, inhibiting the proliferation of drug-resistant and drug-sensitive carcinoma cells.
- Immunogen:
- Antibacterials,Antivirals,Antifungals
- Molecular Weight:
- 3043.6
- Physical State:
- Freeze dried solid
- Purity:
- >95%
- References:
- <p>Li et al (2006) Solution structures of human LL-37 fragments and NMR-based identification of a minimal membrane-targeting antimicrobial and anticancer region. J. Am. Chem. Soc. <strong>12</strong>8(17) 5776 doi:10.1021/ja0584875</p><p> Wu et al (2010) Emerging roles of the host defense peptide LL-37 in human cancer and its potential therapeutic applications. Int. J. Cancer. <strong>127</strong>(8) 1741 doi:10.1002/ijc.25489 </p><p>Wong et al (2011) Antifungal action of human cathelicidin fragment (LL13-37) on Candida albicans. Peptides <strong>32</strong>(10) 1996 https://doi.org/10.1016/j.peptides.2011.08.018</p>
- Sequence:
- H-Ile-Gly-Lys-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Arg-Asn-Leu-Val-Pro-Arg-Thr-Glu-Ser-OH
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Store dark, frozen and desiccated
- Size:
- 1 mg
- Supplier:
- Isca Biochemicals
- Type:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Solubility:
- Soluble in dilute acid
- Formula:
- C137H232N42O36
