CD71 monoclonal antibody (B3-25), InvivoPure
Product Sizes
1 mg
£130.00
AK3641P-1MG
5 mg
£400.00
AK3641P-5MG
25 mg
£1600.00
AK3641P-25MG
50 mg
£2400.00
AK3641P-50MG
100 mg
£3500.00
AK3641P-100MG
About this Product
- SKU:
- AK3641P
- Additional Names:
- Transferrin receptor protein 1, TR, TfR, TfR1, Trfr, T9, p90, Transferrin receptor protein 1, serum form (sTfR), anti-human CD71, Anti-human monoclonal CD71 (TfR1), Anti-human mAb CD71 (TfR1) clone (B3-25), InVivo anti-human CD71.
- Application:
- Cell-based/Functional Assay
- Buffer:
- PBS
- translate.label.attr.clone:
- B3-25
- Clonality:
- Monoclonal
- Concentration:
- 1 mg/ml
- Extra Details:
- The B3/25 antibody targets the human CD71 protein (transferrin receptor), which is critical for cell proliferation and iron uptake. It reduces transferrin binding sites without inhibiting binding and can inhibit the proliferation of human myeloid leukemia cells. In vivo, it suppresses the growth of human melanoma M21 xenografts. B3/25 also interacts with vitronectin receptors on neutrophils, blocking binding to Arg-Gly-Asp (RGD) and inhibiting RGD-stimulated phagocytosis. It precipitates a heterodimer with molecular weights of 140,000 and 105,000 daltons and does not react with gpIIb/III or LFA- 1/Mac-1 receptors. In addition, B3/25 reacts with an acidic glycoprotein on immature and proliferating hematopoietic cells, HeLa cells, and other tumor cell lines, but not on normal human tissues such as brain, kidney, and liver.
- Formulation:
- Clear Liquid, PBS, pH 7.4, 0.2 um sterile filtered
- Host:
- Mouse
- Immunogen:
- Animals were immunized with K-562 cells
- Isotype:
- IgG1, kappa
- Physical State:
- Liquid
- Purity:
- >=90%
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- InVivo Biotech Services GmbH
- Type:
- Antibody: In Vivo Antibodies
