PD-1 monoclonal antibody (29F.1A12)TM, InVivoPure+
Product Sizes
1 mg
£390.00
AK3613PLUS-1MG
5 mg
£600.00
AK3613PLUS-5MG
25 mg
£2100.00
AK3613PLUS-25MG
50 mg
£3600.00
AK3613PLUS-50MG
100 mg
£4100.00
AK3613PLUS-100MG
About this Product
- SKU:
- AK3613PLUS
- Additional Names:
- PD-1, anti-mouse PD1, CD279, programmmed cell death protein 1, Protein PD-1, mPD-1, 29F1A12
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- 29F.1A12TM
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulating T cell exhaustion. Binding of PD-1 to its ligand, programmed death-ligand 1 (PD-L1), activates downstream signaling pathways and inhibits T cell activation. Moreover abnormally high PD-L1 expression on tumor cells and antigen-presenting cells in the tumor microenvironment mediates tumor immune escape, and the development of anti-PD-1/PD-L1 antibodies has recently become a hot topic in cancer immunotherapy. The 29F.1A12 antibody is a monoclonal antibody directed against the mouse protein PD-1 (Programmed Death-1), also known as CD279. It blocks the binding of PD-1 to its two ligands, PD-L1 and PD-L2.
- Formulation:
- Clear Liquid, PBS, pH 7.4, 0.2 um sterile filtered
- Host:
- Rat
- Immunogen:
- The antibody was raised by immunizing rats with plasmid DNA containing PD-1. Boost immunizations were done with PD-1-Igfusion proteins.
- Isotype:
- IgG2a, kappa
- Physical State:
- Liquid
- Purity:
- >=95%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- InVivo Biotech Services GmbH
- Type:
- Antibody: In Vivo Antibodies
- Shipping Costs:
- Free Shipping to the UK
