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Antibodies

HLA DP/DQ/DR monoclonal antibody (IVA12), InVivoPure+

Product Sizes
1 mg
£400.00
AK3601PLUS-1MG
5 mg
£700.00
AK3601PLUS-5MG
25 mg
£2300.00
AK3601PLUS-25MG
50 mg
£4200.00
AK3601PLUS-50MG
100 mg
£5150.00
AK3601PLUS-100MG
About this Product
SKU:
AK3601PLUS
Additional Names:
anti-panHLA-II, anti-panHLA II, Anti-HLA-DP/DQ/DR
Application:
Block/Inhibit/Neutralise
Buffer:
PBS
translate.label.attr.clone:
IVA12
Clonality:
Monoclonal
Concentration:
0.5 mg/ml
Extra Details:
The clone IVA12 recognizes the shared epitopes of human leukocyte antigen (HLA) class II molecules HLA-DP, HLA-DQ and HLA-DR heterodimeric cell surface glycoproteins comprised of an A Alpha (heavy) chain and a B Beta (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional antigen presenting cells (APCs). HLA-Class II expressing APCs specifically present antigens recognized by TCR/CD3 complex of CD4+ T cells. Reactive microglia and perivascular cells in multiple sclerosis lesions express all three types of HLA-Class II molecules, whereas microglia in the normal CNS express HLA-DR only.
Formulation:
Clear Liquid, PBS, pH 7.4, 0.2 um sterile filtered
Host:
Mouse
Immunogen:
Animals were immunized with the Priess human B cell line
Isotype:
IgG1, kappa
Physical State:
Liquid
Purity:
>=95%
Reactivities:
Human
Shipping Conditions:
Blue Ice
Storage Conditions:
Please refer to datasheet
Supplier:
InVivo Biotech Services GmbH
Type:
Antibody: In Vivo Antibodies