Stabilin-2 monoclonal antibody (3.1), InVivoPure
Product Sizes
10 mg
£1144.00
AK2810P-10MG
25 mg
£2470.00
AK2810P-25MG
50 mg
£4225.00
AK2810P-50MG
100 mg
£7020.00
AK2810P-100MG
About this Product
- SKU:
- AK2810P
- Additional Names:
- Feel2, FEX2, FELE-2, FELL2, Stab-2, mStab-2, Stab2 clone 3.1, stabilin-2 clone 3.1, Anti-Mouse Stabilin-2 monoclonal antibody. Anti-Mouse Stabilin-2 clone 3.1.
- Application:
- Block/Inhibit/Neutralise
- Buffer:
- PBS
- translate.label.attr.clone:
- 3.1
- Clonality:
- Monoclonal
- Concentration:
- 0.5 mg/ml
- Extra Details:
- Stabilin-2, also known as Feel2, FEX2, FELE-2, FELL2, is a conserved class H scavenger receptors expressed by sinusoidal endothelial cells (ECs) in the liver, lymph nodes, spleen and bone marrow. Stabilin-2 is the major receptor for hyaluronan; blocking antibodies or genetic ablation of Stabilin-2 inhibits hyaluronan uptake and leads to increased systemic hyaluronan levels. Besides hyaluronan, Stabilin-2 also binds other glycosaminoglycans, including heparin. It is also involved in antisense oligonucleotide pharmacokinetics and nanoparticle uptake, and it controls Von Willebrandt factor-factor VIII complex half-life and immunogenicity. The antibody is suitable material for validation and was used in the following applications: IF; IHC staining of rat, mouse spleen or liver; FACS on stably full length mStab2 transfected HEK293 cells and in in-vivo blocking studies.
- Formulation:
- Clear Liquid, PBS, pH 7.4, 0.2 um sterile filtered
- Host:
- Mouse
- Immunogen:
- Recombinant mouse Stabilin-2 fragment (residues 1-330 of Q8R4U0, fused to mouse IgG2b-Fc)
- Isotype:
- IgG1
- Physical State:
- Liquid
- Purity:
- >=90%
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Storage Conditions:
- Please refer to datasheet
- Supplier:
- InVivo Biotech Services GmbH
- Type:
- Antibody: In Vivo Antibodies
- Shipping Costs:
- Free Shipping to the UK
