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Assay Kits & ELISAs

Near-Infrared DyLight[R] 747 Tracer in vivo Active Caspase (VAD) Assay

Product Sizes
20 tests
£527.00
9114-20TESTS
About this Product
SKU:
9114
Application:
Flow Cytometry, Microscopy
CE/IVD:
RUO
Extra Details:
A fluorescent, cell-permeable tracer for the non-invasive measurement of caspase activity in live animals. The Val-Ala-Asp caspase binding sequence gives the DyLight® 747-VAD-FMK Tracer reagent broad caspase reactivity. Dylight® is a registered trademark of Thermo Fisher Scientific, Inc., ICT
Immunogen:
Poly Caspases
Physical State:
Tissue
Purification:
IN VIVO MONITORING OF APOPTOSIS DURING EXPERIMENTAL ANTI-CANCER TREATMENT, Apoptotic tissues in murine tumor models were imaged in vivo with NIR-FLIVO® 747 Tracer (*Dylight® 747-VAD-FMK, kit #9114) us
Shipping Conditions:
Blue Ice
Storage Conditions:
-20[o]C
Type:
Assay Kits: Cell Viability
Figure 1. Apoptotic tissues in murine tumor models were imaged in vivo with 747-VAD-FMK (cat. 9114). Negative control (placebo) mice (left) and experimentally treated mice (right) were injected intravenously with DyLight® 747-VAD-FMK tracer and imaged non-invasively at various time points with the CRi Maestro™ imaging system. Apoptotic tumor tissues fluoresce bright blue in the experimental group subjects, indicating that the experimental treatment had an apoptotic effect.