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Antibodies

Anti-Human CD28 (IB20) Antibody

Product Sizes
Anti-Human CD28 (IB20) Antibody
£ POA
ICH5023A-0
About this Product
SKU:
ICH5023A-0
Concentration:
5mg/ml
Extra Details:
Theralizumab GN1412 is a humanised monoclonal antibody that not only binds to, but is a strong agonist for, the CD28 receptor of the immune system’s T cells. CD28 is the co-receptor for the T cell receptor; It binds to receptors on the interacting partner in the reaction through one of its ligands (B7 family). It was withdrawn from development after inducing severe inflammatory reactions as well as chronic organ failure in the first-in-human study by PAREXEL in London in March 2006.
Formulation:
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Isotype:
Human IgG4
Purity:
>95% by SDS-PAGE
Purification:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Shipping Conditions:
Blue Ice
Specificity:
Detects human CD28.
Storage Conditions:
This biosimilar is stable when stored at 2-8°C. For longer term storage (> 3 months) it is recommended to store this antibody at -20°C or -70°C.
Supplier:
ichorbio
Type:
Antibodies
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