Ado-Trastuzumab Emtansine Biosimilar - Research Grade
Product Sizes
5mg
ICH4014-5MG
25mg
ICH4014-25MG
200mg
ICH4014-200MG
500mg
ICH4014-500MG
1g
ICH4014-1G
About this Product
- SKU:
- ICH4014
- Additional Names:
- Receptor tyrosine-protein kinase erbB-2, MLN 19, HER2, HER2/neu
- CE/IVD:
- RUO
- Clonality:
- Recombinant Monoclonal
- Concentration:
- 1.0 - 5.0 mg/ml
- Extra Details:
- Ado-trastuzumab emtansine is a HER2-targeted antibody-drug conjugate which contains the humanized anti-HER2 IgG1, trastuzumab, covalently linked to the microtubule inhibitory drug DM1 via the stable thioether linker MCC. Trastuzumab is produced by Chinese hamster ovary cells, and DM1-MCC are produced by chemical synthesis. Ado-trastuzumab emtansine contains an average of 3.5 DM1 molecules per antibody.
- Formulation:
- Phosphate buffered saline (PBS) pH 7.2,with no carrier protein, potassium or preservatives added. BSA and Azide free.
- Host:
- Human
- Immunogen:
- HER2
- Isotype:
- Human IgG1
- Purity:
- >95% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Detects human HER2. This non-therapeutic antibody uses the same sequence as the therapeutic antibody Ado-trastuzumab emtansine.
- Storage Conditions:
- Stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- ichorbio
- Type:
- Antibodies:Monoclonal Antibody
- Shipping Costs:
- Free shipping to UK Customers
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/ado-trastuzumab-emtansine-biosimilar-research-grade/
