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Antibodies

Bispecific Anti-Mouse PD-1 / VEGF-A In Vivo Antibody

Product Sizes
5mg
£820.00
ICH1289-5MG
25mg
£2375.00
ICH1289-25MG
About this Product
SKU:
ICH1289
Application:
In Vivo Administration
translate.label.attr.clone:
RMP1-14 / B20-4.1.1
Concentration:
>1mg/ml
Extra Details:
Our Recombinant Anti-Mouse PD-1 × VEGF-A Bispecific Antibody is a premium preclinical tool engineered to simultaneously target the immune checkpoint pathway and tumor angiogenesis. By combining the variable regions of the industry-standard anti-PD-1 clone RMP1-14 and the pan-VEGF-neutralizing clone B20-4.1.1, this bispecific molecule allows researchers to replicate the dual-pathway mechanism of cutting-edge clinical candidates (such as Ivonescimab / AK112) in standard syngeneic mouse models. Built on a silent Mouse IgG2c LALAPG backbone, this reagent ensures precise pathway blockade without confounding effector-cell mediated toxicities or premature T-cell depletion.
Formulation:
0.2 μM filtered solution of 1x PBS.
Host:
Mouse
Isotype:
Mouse IgG2c LALAPG Kappa
Purity:
>95% by SDS-PAGE under reducing conditions
Purification:
This monoclonal antibody was purified using multi-step affinity chromatography methods such as Protein A or G depending on the species and isotype.
Shipping Conditions:
Blue Ice
Storage Conditions:
This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
Supplier:
ichorbio
Type:
Antibodies:In Vivo Antibodies