Anti-Mouse CD183 (CXCR3-173) In Vivo Antibody - Ultra-Low Endotoxin
Product Sizes
5mg
£429.00
ICH1201UL-5MG
25mg
£1428.00
ICH1201UL-25MG
50mg
£2104.00
ICH1201UL-50MG
100mg
£3012.00
ICH1201UL-100MG
About this Product
- SKU:
- ICH1201UL
- Additional Names:
- CXCR3G, protein-coupled receptor 9 (GPR9), CKR-L2, IP10 receptor (IP10-R), Mig receptor (Mig-R ), CD183
- Application:
- Block/Inhibit/Neutralise
- CE/IVD:
- RUO
- translate.label.attr.clone:
- CXCR3-173
- Clonality:
- Monoclonal
- Concentration:
- ≥ 2.0 mg/ml
- Extra Details:
- Hamsters were tested by ELISA for seropositivity against CXCR3 peptide and hybridomas were generated, screened by FACS, purified, and tested for: staining, CXCR3 blockade in vitro, and endotoxin levels. CXCR3-173 detects the native form of CXCR3, and therefore does not work in Western blotting. CXCR3-173 has potential use in immunotherapeutic approaches to inhibit transplant rejection and immune related diseases. In vitro, CXCR3-173 blocks chemotaxis in response to CXCL10 or CXCL11 but not CXCL9. In vivo, CXCR3-173 prolongs both cardiac and islet allograft survival in a manner further enhanced by rapamycin.
- Formulation:
- Sterile, preservative-free, solution in PBS. BSA and Azide free.
- Host:
- Hamster
- Immunogen:
- CXCR3-173 was generated by immunizing Armenian hamsters with a peptide sequence unique to mouse CXCR3 which encompasses amino acids 1-37.
- Isotype:
- Armenian Hamster IgG
- Purity:
- >98% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- CXCR3-173 activity is directed against murine CD183 (CXCR3).
- Storage Conditions:
- This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- ichorbio
- Type:
- Antibodies:In Vivo Antibodies
- Shipping Costs:
- Free shipping to UK Customers
