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Antibodies

Anti-Mouse CD134 (OX-86) In Vivo Antibody - Ultra-Low Endotoxin

Product Sizes
5 mg
£429.00
ICH1196UL-5MG
25 mg
£1428.00
ICH1196UL-25MG
50 mg
£2104.00
ICH1196UL-50MG
100 mg
£3012.00
ICH1196UL-100MG
About this Product
SKU:
ICH1196UL
Additional Names:
OX-40, TNFRSF4, ACT35
Application:
Activate/Stimulate, Flow Cytometry, Immunohistochemistry, Western Blot
CE/IVD:
RUO
translate.label.attr.clone:
OX-86
Clonality:
Monoclonal
Concentration:
2 mg/ml
Extra Details:
CD134 functions as an important immune checkpoint, and its depletion in murine mouse models demonstrate that lack of CD134 expression leads to reduced CD4+ and CD8+ T cells. When CD134 is bound by its corresponding ligand (OX-40L), an optimal T cell response is generated and plays a significant role in determining the amount of memory T-cells remaining after the immune response. CD134 has also been found to play an important role in carcinogenesis, as treatment with activating in vivo antibodies against CD134 enhanced tumor growth, suggesting that CD134 is an important tumor suppressor, and its absence disrupts the immune response to tumors
Formulation:
Sterile, preservative-free, solution in PBS. BSA and Azide free.
Host:
Rat
Immunogen:
CD134
Isotype:
IgG1
Purity:
>98%
Purification:
This monoclonal antibody was purified using Protein G
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Clone OX-86 reacts with murine CD134 (OX-40, TNFRSF4).
Storage Conditions:
2-8[o]C Aliquot. Avoid freeze/thaw cycles., -70[o]C Aliquot. Avoid freeze/thaw cycles.
Supplier:
ichorbio
Type:
Antibody: Monoclonal Antibody
Shipping Costs:
Free shipping to UK Customers
Main Competition:
This product is an equivalent to the major product in the market