Bulk Anti-Human CD4 (OKT-4) Antibody
Product Sizes
1mg
£131.00
ICH1166-1MG
5mg
£332.00
ICH1166-5MG
25mg
£1057.00
ICH1166-25MG
50mg
£1675.00
ICH1166-50MG
100mg
£2351.00
ICH1166-100MG
About this Product
- SKU:
- ICH1166
- Application:
- Block/Inhibit/Neutralise
- CE/IVD:
- RUO
- translate.label.attr.clone:
- OKT-4
- Clonality:
- Monoclonal
- Concentration:
- 1mg/ml
- Extra Details:
- Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. LCK then initiates different intracellular signaling pathways by phosphorylating various substrates ultimately leading to lymphokine production, motility, adhesion and activation of T-helper cells. In other cells such as macrophages or NK cells, plays a role in differentiation/activation, cytokine expression and cell migration in a TCR/LCK-independent pathway. Participates in the development of T-helper cells in the thymus and triggers the differentiation of monocytes into functional mature macrophages. (Microbial infection) Primary receptor for human immunodeficiency virus-1 (HIV-1). Down-regulated by HIV-1 Vpu. Acts as a receptor for Human Herpes virus 7/HHV-7.
- Formulation:
- This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added. BSA and a
- Host:
- Mouse
- Immunogen:
- Human peripheral T cells
- Isotype:
- Mouse IgG2b Kappa
- Purity:
- >95% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Human
- Shipping Conditions:
- Blue Ice
- Specificity:
- Clone OKT4 recognizes Human CD4. This clone recognizes a different epitope than the RPA-T4 monoclonal antibody, and these antibodies do not interfere with each other
- Storage Conditions:
- This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- ichorbio
- Type:
- Antibodies
- Shipping Costs:
- Free shipping to UK Customers
- Main Competition:
- This product is an equivalent to the major product in the market
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/anti-human-cd4-in-vivo-antibody-low-endotoxin-okt-4-ich1166/
