Anti-Mouse TCR Beta (H57-597) Antibody In Vivo Antibody - Ultra-Low Endotoxin
Product Sizes
5mg
£429.00
ICH1153UL-5MG
25mg
£1428.00
ICH1153UL-25MG
50mg
£2104.00
ICH1153UL-50MG
100mg
£3012.00
ICH1153UL-100MG
About this Product
- SKU:
- ICH1153UL
- Additional Names:
- TCR-B Beta chain, TCR-B Beta, B Beta-TCR
- Application:
- Depletion
- CE/IVD:
- RUO
- translate.label.attr.clone:
- H57-597
- Clonality:
- Monoclonal
- Concentration:
- ≥ 5.0 mg/ml
- Extra Details:
- TCRβ antibody, clone H57-597, recognizes the beta chain of the T cell receptor (TCRβ), expressed on αβ thymocytes and T lymphocytes, as well as natural killer T (NKT) cells. TCRβ is a transmembrane protein that consists of an amino-terminal variable region, a constant region, and a stalk segment covalently linked to the TCR alpha chain (TCRα) via a disulfide bond. TCRα/β does not contain signaling domains and is instead noncovalently associated with the CD3 complex (TCR-CD3), essential for TCR signaling. TCRα/β recognizes antigens bound to major histocompatibility complex (MHC) molecules, resulting in phosphorylation of CD3 ITAMs and subsequent T cell activation, proliferation, and survival.
- Formulation:
- This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
- Host:
- Hamster
- Immunogen:
- Affinity purified TCR from mouse DO-11.10 cells
- Isotype:
- Armenian Hamster IgG
- Purity:
- >98% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Clone H57-597 recognizes an epitope on the constant region of mouse TCRβ. Clone H57-597 does not cross-react with γδ T cells.
- Storage Conditions:
- This antibody is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C. Avoid Repeated Freeze Thaw Cycles.
- Supplier:
- ichorbio
- Type:
- Antibodies:In Vivo Antibodies
- Shipping Costs:
- Free shipping to UK Customers
