Anti-Mouse IFNAR1 (MAR1-5A3) In Vivo Antibody - Low Endotoxin
Product Sizes
1mg
£119.00
ICH1122-1MG
5mg
£332.00
ICH1122-5MG
25mg
£1057.00
ICH1122-25MG
50mg
£1675.00
ICH1122-50MG
100mg
£2351.00
ICH1122-100MG
500mg
£10325.00
ICH1122-500MG
1g
£18675.00
ICH1122-1G
About this Product
- SKU:
- ICH1122
- Additional Names:
- Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Type I interferon receptor 1, Ifar, Ifnar
- Application:
- Block/Inhibit/Neutralise
- CE/IVD:
- RUO
- translate.label.attr.clone:
- MAR1-5A3
- Clonality:
- Monoclonal
- Concentration:
- ≥ 2.0 mg/ml
- Extra Details:
- The antibody when prepared specifically for In vivo functional assays blocks type I IFN receptor signaling both In vitro and In vivo without depleting IFNAR1 bearing cells. This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1. IFNAR1 and IFNAR2 are coexpressed on nearly all cells and make up the heterodimeric receptor that binds all type I IFNs (IFN alpha and beta). Type I IFNs are a family of cytokines that have been shown to promote anti-viral, anti-microbial, anti-tumor and autoimmune responses In vivo.
- Formulation:
- 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Host:
- Mouse
- Immunogen:
- This antibody was produced by In vivo genetic immunization of IFNAR1 knockout mice with a plasmid encoding the extracellular domain of murine IFNAR1.
- Isotype:
- Mouse IgG1
- Purity:
- >95% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-IFNAR1 In Vivo Antibody - Low Endotoxin (MAR1-5A3) recognizes the extracellular domain of the IFNAR1 subunit of the mouse IFN-alpha / beta receptor.
- Storage Conditions:
- anti-IFNAR1 In Vivo Antibody - Low Endotoxin (MAR1-5A3) is stable for at least four (4) weeks when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –80°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. NOTE: Do not freeze as this antibody at -20°C as this clone will sometimes precipitate over long period of time.
- Supplier:
- ichorbio
- Type:
- Antibodies:In Vivo Antibodies
- Shipping Costs:
- Free shipping to UK Customers
- Main Competition:
- This product is an equivalent to the major product in the market
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/Anti-IFNAR1-In-Vivo-Antibody-Low-Endotoxin-MAR1-5A3-ICH1122/
