Anti-Mouse IL-1R (JAMA-147) In Vivo Antibody - Low Endotoxin
Product Sizes
1mg
ICH1117-1MG
5mg
ICH1117-5MG
25mg
ICH1117-25MG
50mg
ICH1117-50MG
100mg
ICH1117-100MG
About this Product
- SKU:
- ICH1117
- Additional Names:
- Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a
- Application:
- Block/Inhibit/Neutralise
- CE/IVD:
- RUO
- translate.label.attr.clone:
- JAMA-147
- Clonality:
- Monoclonal
- Concentration:
- 1.0 - 5.0 mg/ml
- Extra Details:
- IL-1 binds two receptors, IL-1RI and IL-1RII. The ligands IL-1alpha and IL-1beta exert all of their various biological actions by binding IL-1RI. IL-1RII has a shortened cytoplasmic domain that is unable to transduce signals and therefore acts as a decoy receptor and competitively antagonizes the binding of IL-1alpha and IL-1beta, thereby reducing their biological effects. Binding of the ligands to IL-1RI is enhanced by an accessory protein, IL-1R-AcP. IL-1RI is expressed on T cells, thymocytes, dendritic cells, fibroblasts, vascular endothelial cells, epithelial cells and neural cells. It is an 80 kD transmembrane glycoprotein.
- Formulation:
- 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Host:
- Hamster
- Immunogen:
- Extracellular domain of mouse IL-1 R type 1
- Isotype:
- Armenian Hamster IgG
- Purity:
- >95% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein A
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) recognizes Mouse IL-1 R1
- Storage Conditions:
- anti-IL-1R In Vivo Antibody - Low Endotoxin (JAMA-147) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles
- Supplier:
- ichorbio
- Type:
- Antibodies:In Vivo Antibodies
- Shipping Costs:
- Free shipping to UK Customers
- Main Competition:
- This product is an equivalent to the major product in the market
