Anti-Mouse RANKL (IK22/5) In Vivo Antibody - Ultra-Low Endotoxin
Product Sizes
5mg
£429.00
ICH1114UL-5MG
25mg
£1428.00
ICH1114UL-25MG
50mg
£2104.00
ICH1114UL-50MG
100mg
£3012.00
ICH1114UL-100MG
About this Product
- SKU:
- ICH1114UL
- Additional Names:
- Tumor necrosis factor ligand superfamily member 11, Tnfsf11, Osteoclast differentiation factor, ODF, Osteoprotegerin ligand, OPGL, Receptor activator of nuclear factor kappa-B ligand, TNF-related activation-induced cytokine, TRANCE, CD254
- Application:
- Block/Inhibit/Neutralise
- CE/IVD:
- RUO
- translate.label.attr.clone:
- IK22/5
- Clonality:
- Monoclonal
- Concentration:
- 1.0 mg/ml
- Extra Details:
- RANKL (Receptor Activator for Nuclear Factor κ B Ligand), also known as TNF-related activation-induced cytokine (TRANCE), osteoprotegerin ligand (OPGL), and ODF (osteoclast differentiation factor), is a member of the tumor necrosis factor family cytokine. RANKL is essential for osteoclast formation, activation, and survival. RANKL through interaction with its receptor RANK can modulate matrix degradation and inflammation. RANKL and RANK have essential roles in lymph node formation, establishment of the thymic microenvironment, and development of a lactating mammary gland during pregnancy. Consequently, novel drugs specifically targeting RANK, RANKL, and their signaling pathways in osteoclasts are expected to revolutionize the treatment of various ailments associated with bone loss, such as arthritis, periodontal disease, cancer metastases, and osteoporosis.
- Formulation:
- 0.01 M phosphate buffered saline (PBS) pH 7.2, 150 mM NaCl with no carrier protein, potassium or preservatives added.
- Host:
- Rat
- Immunogen:
- Purified Recombinant Mouse RANKL (NSO-derived)
- Isotype:
- Rat IgG2a Kappa
- Purity:
- >98% by SDS-PAGE and HPLC
- Purification:
- This monoclonal antibody was purified using Protein G
- Reactivities:
- Mouse
- Shipping Conditions:
- Blue Ice
- Specificity:
- Anti-RANKL In Vivo Antibody - Ultra-Low Endotoxin (IK22/5) recognizes an epitope on Mouse RANKL
- Storage Conditions:
- anti-RANKL In Vivo Antibody - Low Endotoxin (IK22/5) is stable when stored at 2-8°C. Do not freeze.This antibody is
- Supplier:
- ichorbio
- Type:
- Antibodies:In Vivo Antibodies
- Shipping Costs:
- Free shipping to UK Customers
- Manufacturer's Data Sheet:https://ichor.bio/productpdf/print/index/url_key/5-ICH1114/
