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Antibodies

Anti-Mouse IL-1b (B122) In Vivo Antibody - Low Endotoxin

Product Sizes
1mg
£131.00
ICH1100-1MG
5mg
£332.00
ICH1100-5MG
25mg
£1057.00
ICH1100-25MG
50mg
£1675.00
ICH1100-50MG
100mg
£2351.00
ICH1100-100MG
About this Product
SKU:
ICH1100
Additional Names:
Interleukin-1 beta, IL-1B
Application:
Block/Inhibit/Neutralise
CE/IVD:
RUO
translate.label.attr.clone:
B122
Clonality:
Monoclonal
Concentration:
1.0 mg/ml
Extra Details:
Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β.
Formulation:
0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium or preservatives added.
Host:
Hamster
Immunogen:
E. coli -expressed, recombinant mouse IL-1B Beta
Isotype:
Armenian Hamster IgG
Purity:
>95% by SDS-PAGE and HPLC
Purification:
This monoclonal antibody was purified using Protein A
Reactivities:
Mouse
Shipping Conditions:
Blue Ice
Specificity:
Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) recognizes Mouse IL-1B
Storage Conditions:
anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) is stable for at least one week when stored sterile at 2-8°C. For long term storage aseptically aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Supplier:
ichorbio
Type:
Antibodies:In Vivo Antibodies
Shipping Costs:
Free shipping to UK Customers
Main Competition:
This product is an equivalent to the major product in the market